MLB DFS Picks, Spotlight Pitchers & Top Stacks: Attack of the G-Men! (Sept. 25)

Wednesday brings a nifty nine-game featured slate locking with a 7:05 p.m. ET first pitch on DraftKings, FanDuel and Yahoo. Today we’re exploring the MLB DFS projections with Stokastic’s industry-leading tools to uncover how to build MLB DFS stacks, find top pitchers and craft optimal daily fantasy baseball lineups. Zac Gallen and Kevin Gausman are rising above the fray for the pitching options tonight, while Stokastic’s MLB DFS Top Stacks Tool likes the Arizona Diamondbacks, along with the Coors Field Extravaganza, as key MLB DFS picks.

MLB DFS Picks: Spotlight Pitchers and Top Stacks | Sept. 25

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MLB DFS Picks: Spotlight Pitchers

Main Slate Primary Pitching Target: RHP Zac Gallen (ARZ vs. SF)

Diamondbacks vs. Giants – 3.5 implied runs
First Pitch: 9:40 p.m. ET
$9,000 at DraftKings
$9,800 at FanDuel
$45 at Yahoo

The Stokastic MLB DFS Top Pitchers tool likes LHP Chris Sale against the New York Mets, though there is a high probability of rain in Atlanta throughout tonight. RHP Jack Flaherty would move up from the mid-tier to a coveted option, if San Diego were to run out some extra reserves tonight after clinching a postseason slot, though the team still can improve playoff seeding, so that is unlikely.

That brings RHP Zac Gallen to the forefront, against a pesky San Francisco squad. The strength of Gallen’s game is his run-prevention. For his career, he has a 3.30 ERA across 142 starts, and while his 3.74 ERA this season is his second highest mark, it would still land him inside the top-35 pitchers, if he had a few more innings to his credit.

Gallen has seen is strikeouts slide down to 9.2 per nine innings this season, a personal low and he has been below 10.3 per nine each of the last three campaigns. Over the last two months, the Giants have been within hailing distance of league average runs per game, but nothing too special. The projected lineup for tonight does have a 25.9% strikeout rate against right-handed pitching, which is higher than what we typically see from this platoon-heavy squad. Projecting a win is usually folly, though it is nice to see that Arizona is -225 money line home favorites to garner the victory tonight.

Main Slate Secondary Pitching Target: RHP Kevin Gausman (TOR vs. BOS)

Blue Jays vs. Red Sox – 3.9 implied runs
First Pitch: 7:07 p.m. ET
$8,600 at DraftKings
$9,000 at FanDuel
$44 at Yahoo

On Jun. 30, RHP Kevin Gauman was a gas can, getting light up for seven runs by the New York Yankees. Since then, he has logged 13 appearances and 84 innings, with a 3.00 ERA, 3.47 FIP and a 4.55 xFIP.

Though he has nearly three walks per nine innings in this stretch, he has ceded only half a dozen home runs. The biggest concern is that he has only 7.3 strikeouts per nine innings, though that has increased to 8.2 per nine, when looking at his last five appearances.

Boston of course is without Rafael Devers, who was finally shut down with a sore shoulder that was impacting his swing and of course his power. That means more Triston Casas 31.7% strikeout rate, in 161 PAs against right-handed pitching this season. Trevor Story (28.6%, 70 PAs) is healthy for the moment, Connor Wong (24.6%, 325 PAs) should be behind the plate and Wilyer Abreu (28.8%, 368 PAs) is like a wind machine.

MLB DFS Picks: Top Stacks

Main Slate Primary Target: Arizona Diamondbacks

Diamondbacks vs. Giants – 5.1 implied runs
First Pitch: 9:40 p.m. ET
Opposing Starter: RHP Mason Black
DK Top Stack %: 9.2%
FD Top Stack %: 9.3%

The Stokastic MLB DFS Top Stacks Tool has the Coors Field Extravaganza with jost over a 25% probability of producing the highest scoring fantasy team of the night.

The Diamondbacks are slotting in between the Cardinals and Rockies, making them a terrific countermove to that matchup in the thin Denver air.

Rookie RHP Mason Black is the 15th best prospect for San Francisco, though he is not on any of the industry top-100 lists.

He is getting a cup of coffee to close out the season, with a decent chance of making the 2025 Opening Day roster.

Last year he was promoted to Triple-A midseason and that is where he resumed his baseball journey this year. Most projection systems have him as a solid fourth or fifth starter. He probably would be a reliever, if he had a better fastball, but there is still plenty of opportunity and value for a combo pitcher, who has a good breaking ball and can take the mound once a week.

The lack of strikeouts, means plenty of hard contact and Black does have a 1.87 home runs per nine innings rate, during his brief time in The Show. Of course, going against the Diamondbacks is always a scary situation, with the team leading the league in runs scored on the season (5.46 rpg), since the All-Star Break (6.26 rpg) and in September (6.13 rpg).

Riding with the usual suspects is a savvy strategy, with Corbin Carroll, Joc Pederson, Ketel Marte and Christian Walker comprising the core four. Veteran basher Eugenio Suarez is the perfect player to round out full stacks, with a strong profile against Black’s offerings.

Main Slate Wild Card Target: Los Angeles Angels

Angels at White Sox – 4.0 implied runs
First Pitch: 7:40 p.m. ET
Opposing Starter: RHP Davis Martin
DK Top Stack %: 5.5%
FD Top Stack %: 5.4%

Clearly this is a top heavy slate, with three teams dominating the top-stack probability. However, there are a couple of intriguing Los Angeles options, so a mini-stack for differentiation is in play.

RHP Davis Martin has been meh, over his last four starts, with a 6.16 EA, 4.69 FIP and 4.24 xFIP. He has 19 innings in this stretch, with 17 strikeouts, with a trio of taters. Between the pandemic and Tommy John surgery, Martin missed his 2023 projected arrival to The Show. The former 14th round selection of the 2017 MLB Draft is nothing special, but he also is not completely dreadful.

That is why being selective with some Halos, is a decent under the radar strategy, that does have upside. Anaheim has not had injury luck with Mike Trout, who was limited to just 29 games this season and 266 over the last four. Then letting Shohei Ohtani go to the Dodgers in free agency, well it is hard to begrudge them for not wanting to shovel away a mountain of money, but what a season it has been for the reigning AL MVP.

Then there were injuries to half a dozen regulars, in addition to Trout, which has had the DFS world rightfully picking on the Angels for significant portions of the season. Tonight we can look to two or three of Taylor Ward, Zach Neto, Logan O’Hoppe, Mickey Moniak and Eric Wagaman as differentiation plays. Again DO NOT GO OVERBOARD, but a sprinkling here and there is just right.

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Final Thoughts for Wednesday, Sept. 25

There is potential precipitation risk for the early MLB action. For the featured slate, only Atlanta and Chicago need to be monitored, with potential for an in-game delay. Before locking in your MLB DFS picks, make sure to visit the top MLB Weather Report page for the latest updates as game time nears.

Eric "EMac" MacPherson won the 2007 Fantasy Baseball grand prize (trip for two to the MLB All-Star game) in the Roto format on ESPN. He won again in 2008, this time in the H2H format. As one of the early adopters of daily fantasy sports, EMac has been providing content for baseball and basketball as well as both professional and college football since 2012 for a variety of websites including DraftKings Playbook, FanVice, RotoWorld, Daily Fantasy Bootcamp, and RotoGrinders. He is well into his third decade of fantasy sports and has a wealth of knowledge and experience. Follow him on Twitter @EMacDFS or contact EMac by emailing [email protected].

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